Background and Purpose: Cancer is a chronic disease that causes many patient issues and concerns. Death anxiety and problem-solving are seen in these patients. In the present study, neurofeedback training (NFT) is a non-invasive method. This study aimed to determine the effectiveness of NFT on death anxiety and to problem-solving in cancer patients.

Method: The present research is a quasi-experimental study with a pretest-posttest-follow-up design and two experimental and control groups. Individuals were randomly assigned to each group. The sample included 32 breast and ovarian cancer patients under chemotherapy in Rafsanjan city in 2021. The Participants completed the death anxiety questionnaire (Templer, 1970) and the Problem-solving inventory (Heppner and Petersen, 1982). Data were analyzed with the analysis of covariance in SPSS software.

Finding: The results showed that NFT had been an effective method for death anxiety and four subscales of problem-solving, including sensation, intuition, feeling, and thinking at posttest and follow-up (p<0.05).

Conclusion: It can be concluded that neurofeedback intervention therapy has effectively reduced death anxiety and increased problem-solving skills, and psychologists can use this method.